Antidepressants can definitely be a contributor to weight gain. This study confirms what I have seen in my practice: escitalopram (lexapro) is one of the most weight gaining antidepressants. It's also a really Stopping Zepbound: what happens and how to keep the weight off Sword Health GLP 1 Weight Loss in Colorado Springs Studies: Regardless of starting weight, Zepbound helps obese people shed pounds UPI.com Zepbound (Tirzepatide), The FDA Approved Weight Loss Drug That Treats Sleep Apnea Zepbound leads to more weight loss than Wegovy, drugmaker Eli Lilly says CNN