When Brilliance and Madness Collide - Paperbackby Ruth Manning (Author) When Brilliance & Madness Collide is a personal account of Ruth Manning, PhD, who has struggled with bipolar I disorder for the majority of her adult life. Her career path has had a myriad of twists and turns, from serving as founder and CEO of a biotech DNA sequence analysis software company, to working at a US national laboratory, to teaching mathematics as a university professor. These professional successes are