FRONTLINE Plus for Medium Dogs (23-44 lbs) Flea and Tick Treatment 3 DosesFRONTLINE Plus for Medium Dogs (23 44 lbs) Flea and Tick Treatment 3 Doses. Give your furry buddy the relief he or she needs from parasites with the help of the FRONTLINE Flea And Tick For Dogs (23 44 lbs). This product is specially formulated with two tough killing ingredients: fipronil and (S) methoprene one to kill adult flees and ticks and the other to get rid of flea eggs and larvae. This fast acting flea tick FRONTLINE Plus dogs is easy to apply